Human transcriptome - molecular neurobiology
نویسندگان
چکیده
منابع مشابه
Molecular Neurobiology of Human Cognition
Recent studies into human mental retardation syndromes have given new insights into the molecular underpinnings of human cognitive processing, in particular into mechanisms likely to contribute to learning and memory. In this minireview, we present an overview of one signal transduction cascade that has garnered attention of late in this context, the ras/ERK/CREB pathway. We focus on this casca...
متن کاملMolecular neurobiology of mTOR
Mammalian/mechanistic target of rapamycin (mTOR) is a serine-threonine kinase that controls several important aspects of mammalian cell function. mTOR activity is modulated by various intra- and extracellular factors; in turn, mTOR changes rates of translation, transcription, protein degradation, cell signaling, metabolism, and cytoskeleton dynamics. mTOR has been repeatedly shown to participat...
متن کاملFluorescence Applications in Molecular Neurobiology
Macromolecules drive the complex behavior of neurons. For example, channels and transporters control the movements of ions across membranes, SNAREs direct the fusion of vesicles at the synapse, and motors move cargo throughout the cell. Understanding the structure, assembly, and conformational movements of these and other neuronal proteins is essential to understanding the brain. Developments i...
متن کاملThe emergence of molecular neurobiology
The dramatic changes in neuroscience research are conveniently illustrated by comparing the contents of the two most recent Cold Spring Harbor Symposia in 1975 and 1984. In 1975, neurobiology was a field of infinite promise, already attracting able young scientists from molecular biology and physics, but quite limited in the number of questions that could be addressed on the molecular level. Th...
متن کاملNeurobiology of Disease Presenilin-1-Dependent Transcriptome Changes
Károly Mirnics,1,2* Zeljka Korade,3* Dominique Arion,1 Orly Lazarov,4 Travis Unger,1 Melissa Macioce,1 Michael Sabatini,1,2 David Terrano,4 Katherine C. Douglass,1 Nina F. Schor,3 and Sangram S. Sisodia4 Departments of 1Psychiatry, 2Neurobiology, and 3Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, and 4Center for Molecular Neurobiology, University of Ch...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gyrus
سال: 2015
ISSN: 1849-5427
DOI: 10.17486/gyr.3.1031